Container Closure Integrity Testing (CCIT)

CCIT micro-hole drilling operations are handled by Goodfellow's advanced microfabrication division in Baltimore, MD.

Goodfellow’s CCIT services enable clients to replicate real-world defects in packaging materials with exceptional precision. Using advanced laser microfabrication technology, we can create micro-holes as small as 1 µm* in glass and polymer containers, accurately simulating cracks, pinholes, or other imperfections encountered during production.

Each defect is tailored to customer requirements and supplied with a Certificate of Conformance and Quality Data Sheet. Our capabilities extend to a variety of packaging formats, including:

• Glass and polymer vials

• Ampoules

• Foil and blister packs

• Pouches and bags (filled or unfilled)

• Metal and sealed containers

Our hole placement accuracy, NIST-traceable calibration standards, and ISO 13485-certified processes ensure consistency, reproducibility, and traceable quality across every project.

*Dependant on material and thickness. Standard achievable target around 2 µm (tolerance +2/−1 µm)

To complement our defect creation expertise, we offer complete testing and validation capabilities through our integrated Goodfellow group facilities.

• Precision laser drilling of the defects.

• Analytical testing and verification of container closure integrity using advanced, non-destructive methodologies.

These capabilities allow us to deliver end-to-end CCIT support, from the creation of calibrated standards to the validation of closure integrity performance.

Our CCIT solutions serve industries where package integrity and sterility are mission-critical:

• Pharmaceuticals – Validation of vial and syringe closure systems

• Medical Devices – Packaging verification for sterile products

• Biotechnology – Testing of containment systems and diagnostic cartridges

• Food & Packaging – Quality control for sealed packaging and barrier materials

By combining the expertise and capabilities of our different facilities, we provide a single, trusted source for CCIT services, ensuring consistent quality, validated performance, and fast turnaround times.

Benefits include:

• Controlled defects down to 2 µm (tolerance +2/−1 µm); 1 µm precision achievable for certain materials and thicknesses

• ISO 13485-certified processes

• NIST-traceable calibration

• Realistic defect simulation for accurate testing

• Rapid project turnaround

• Comprehensive documentation and traceability

Whether you require calibrated micro-defects for CCIT validation, or a fully integrated testing and analysis program, Goodfellow provides the expertise and global infrastructure to support your quality assurance needs.